EMERGENCE OF MEMBERS OF TRAF AND DUB OF UBIQUITIN PROTEASOME SYSTEM IN THE REGULATION OF HYPERTROPHIC CARDIOMYOPATHY

Emergence of Members of TRAF and DUB of Ubiquitin Proteasome System in the Regulation of Hypertrophic Cardiomyopathy

The ubiquitin proteasome system (UPS) plays an imperative role in many critical cellular processes, frequently by mediating the selective degradation of misfolded and damaged proteins and also by playing a non-degradative role especially important as in many signaling pathways.Over the last three decades, accumulated evidence indicated that UPS pro

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Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs

IL-1 family member IL-33 exerts a variety of immune activating and regulating properties and has recently been proposed as a prognostic biomarker for cancer diseases, although its precise role in tumor immunity is unclear.Here we analyzed in vitro conditions influencing the function of IL-33 as an alarmin and a co-factor for the activity of cytotox

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Reestruturação intraurbana de cidades médias

Este artigo tem por objetivo analisar a disseminação de shopping centers e condomínios fechados de alta renda em cidades médias, a partir dos casos das cidades de Caxias do Sul, Passo Fundo, Pelotas e Santa Maria, localizadas no estado do Rio Grande do Sul.A emergência desses espaços, por um lado, associa-se Screens a estratégias capitalista

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